| 发明名称 |
Delivery of cytotoxic agents. |
| 摘要 |
<p>Provided is a means for delivery of a cytotoxic agent which is useful in the treatment of neoplastic diseases. In particular, Antibody-Enzyme Conjugates and Substrate-Cytotoxic Agent compounds are disclosed.</p> |
| 申请公布号 |
EP0382411(A2) |
申请公布日期 |
1990.08.16 |
| 申请号 |
EP19900301072 |
申请日期 |
1990.02.01 |
| 申请人 |
ELI LILLY AND COMPANY;HYBRITECH INCORPORATED |
发明人 |
CHEN, VICTOR JOHN;JUNGHEIM, LOUIS NICKOLAUS;MEYER, DAMON LAWRENCE;SHEPHERD, TIMOTHY ALAN |
| 分类号 |
A61K31/70;C12N9/00;A61K31/545;A61K31/546;A61K31/7028;A61K31/7034;A61K31/704;A61K31/7042;A61K31/7048;A61K31/7052;A61K31/7064;A61K31/7068;A61K38/00;A61K39/395;A61K45/00;A61K47/48;A61P35/00;C07D207/28;C07D501/00;C07D519/04;C07H15/252;C07K14/00;C07H15/26;C07H17/04;C07H19/06;C07K16/00;C07K19/00 |
主分类号 |
A61K31/70 |
| 代理机构 |
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