发明名称 Treatment of autoimmune diseases with the morpholinoethyl ester of mycophenolic acid, and derivatives thereof
摘要 The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or -C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, particularly for treatment of allograft rejection, especially including cardiac allograft rejection, pancreatic allograft rejection and renal allograft rejection, and for treating autoimmune diabetes. <IMAGE> (Formula A)
申请公布号 US4948793(A) 申请公布日期 1990.08.14
申请号 US19890373413 申请日期 1989.06.29
申请人 SYNTEX (U.S.A.) INC. 发明人 ALLISON, ANTHONY C.;EUGUI, ELSIE M.;NELSON, PETER H.;GU, CHEE-LIANG L.;LEE, WILLIAM A.
分类号 C07D307/88 主分类号 C07D307/88
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