OXIDATION OF 2-ARYLPROPANALS

摘要

2-(4-isobutylphenol) propionic acld (*ibuprofen and other 2-aryl propionic acids useful as analgesic and anti-inflammatory agents, are produced by oxidation of the corresponding 2-aryl propionaldehydes with oxygen in the presence of soluble manganese or cobalt catalysts, with high selectivities with soluble manganese salts, or with soluble cobalt salts along with sodium salts. *Trademark