发明名称 NEW SUBSTANCE UCT-1003 AND PRODUCTION THEREOF
摘要 NEW MATERIAL:UCT-1003 expressed by the formula having the following physicochemical properties. Molecular formula, C18H10O7; molecular weight, 338; melting point, gradually blackened and exhibiting no apparent melting point; solubility to solvent, readily soluble in DMSO, methanol, ethanol and acetone, soluble in chloroform and ethyl acetate and slightly soluble in water and n-hexane; color of substance and appearance, deep rod-purple powder, etc. USE:A medicine. An antiulcer agent having antimicrobial action and antitumor action. PREPARATION:A microorganism (spc-13780 strain, FERM P-2256) collected and separated from soil in Yamanashi prefecture, belonging to the genus Pacilomyces and having ability capable of producing UCT-1003 is subjected to liquid culture in a medium of pH4-10 containing ammonia water, ammonium carbonate solution, etc., at 20-35 deg.C for 1-7 day and separation and purification normally used for cultured product is carried out to isolate UCT-1003 expressed by the formula.
申请公布号 JPH02200655(A) 申请公布日期 1990.08.08
申请号 JP19890018300 申请日期 1989.01.27
申请人 KYOWA HAKKO KOGYO CO LTD 发明人 NAKANO HIROFUMI;YAMASHITA YORINORI;ANDO KATSUHIKO;SAITO YUTAKA;TAKAHASHI KEIICHI;OONO HIROSHIGE
分类号 C07C50/36;C12P29/00;C12R1/645 主分类号 C07C50/36
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