摘要 |
NEW MATERIAL:UCT-1003 expressed by the formula having the following physicochemical properties. Molecular formula, C18H10O7; molecular weight, 338; melting point, gradually blackened and exhibiting no apparent melting point; solubility to solvent, readily soluble in DMSO, methanol, ethanol and acetone, soluble in chloroform and ethyl acetate and slightly soluble in water and n-hexane; color of substance and appearance, deep rod-purple powder, etc. USE:A medicine. An antiulcer agent having antimicrobial action and antitumor action. PREPARATION:A microorganism (spc-13780 strain, FERM P-2256) collected and separated from soil in Yamanashi prefecture, belonging to the genus Pacilomyces and having ability capable of producing UCT-1003 is subjected to liquid culture in a medium of pH4-10 containing ammonia water, ammonium carbonate solution, etc., at 20-35 deg.C for 1-7 day and separation and purification normally used for cultured product is carried out to isolate UCT-1003 expressed by the formula. |