发明名称 Cis-imidazolines
摘要 There are presented compounds of the formula or pharmaceutically acceptable salts thereof, wherein Y1, Y2, X1, X2, X3 and R are as described in this application. These compounds are believed to inhibit MDM2-p53 interaction and as such the compounds will have anti-hyperproliferative cellular activity.
申请公布号 US7579368(B2) 申请公布日期 2009.08.25
申请号 US20060374407 申请日期 2006.03.13
申请人 HOFFMAN-LA ROCHE INC. 发明人 FOTOUHI NADER;HALEY GREGORY JAY;SIMONSEN KLAUS B.;VU BINH THANH;WEBBER STEPHEN EVAN
分类号 A61K31/4164;C07D233/08 主分类号 A61K31/4164
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