发明名称 DERIVES GLYCOSYL PHOSPHOLIPIDIQUES DE NUCLEOSIDES ET LEUR APPLICATION EN TANT QUE MEDICAMENTS
摘要 The glycosyl phospholipid nucleoside derivatives of the invention are based on the formula (I) in which R3 is a group (II) in which "ose" is a sugar structure at C5 or C6, D or L, except for glucose when x is equal to 1, the phosphoryl substitution chain being fixed in position 1 or 6 of the "ose" structure to which it is attached, x is a number from 1 to 12, y is a number from 1 to 4; z is equal to 0 or 1, A is: hydrogen or an alc. group of 5 to 30 carbon atoms; R1 is: hydrogen, C1 to C4 alkyl, halogen, nitrile or hydroxyl and R2 is: C1 to C4 alkyl, halogen or nitrile. These derivatives are useful for producing pharmaceutical compositions having, in particular, anti-viral properties.
申请公布号 FR2642428(A1) 申请公布日期 1990.08.03
申请号 FR19890001134 申请日期 1989.01.30
申请人 PASTEUR INSTITUT 发明人 TAM HUYNH DINH;CATHERINE GOUYETTE;JEAN IGOLEN;ROBERT FAUVE;LUC MONTAGNIER;YVETTE HENIN;OLIVIER SCHWARTZ
分类号 A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7072;A61P31/12;C07H19/10;(IPC1-7):C07H19/10 主分类号 A61K31/70
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