| 摘要 |
This invention relates to the use of heparin fragment showing complement inhibition activity and reduced bleeding time when compared to heparin regardless of anticoagulant activity for the manufacturing of medicaments for treating pathological inflammations as well as the method for treatment of pathological inflammations by administration of the heparin fragment. The invention also relates to a method for finding heparin fragments with high therapeutical value by choosing those with short bleeding time and high complement inhibition activity regardless of anticoagulant activity. Another aspect of the invention is the heparin fragment showing complement inhibition activity and reduced bleeding time when compared to heparin regardless of anticoagulant activity and pharmaceutical compositions containing them. The invention also relates to the process for the preparation of heparin fragments. |
