发明名称 |
Imidazolone derivatives with activity on central nervous system and antihypertensive activity, preparation methods thereof, and pharmaceutical compositions containing them. |
摘要 |
<p>Invention concerns 4,5-bisubstituted-2-imidazolone derivatives of formula I <CHEM> and pharmaceuticaily acceptable salts thereof, having high affinity in vitro for D2, 5-HT2, 1 receptors and in vivo activity on central nervous system and antihypertensive activity with negligible secondary effects; methods for the preparation thereof; pharmaceutical formulations containing them.</p> |
申请公布号 |
EP0379990(A1) |
申请公布日期 |
1990.08.01 |
申请号 |
EP19900101080 |
申请日期 |
1990.01.19 |
申请人 |
ISTITUTO LUSO FARMACO D'ITALIA S.P.A. |
发明人 |
SALIMBENI, ALDO;CASCIO, GIUSEPPE;MANGHISI, ELSO |
分类号 |
A61K31/41;A61K31/4427;A61K31/455;A61K31/495;A61P9/00;A61P9/12;A61P25/18;A61P25/20;A61P25/24;A61P25/26;C07D233/70;C07D401/06;C07D401/14 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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