发明名称 Imidazolone derivatives with activity on central nervous system and antihypertensive activity, preparation methods thereof, and pharmaceutical compositions containing them.
摘要 <p>Invention concerns 4,5-bisubstituted-2-imidazolone derivatives of formula I &lt;CHEM&gt; and pharmaceuticaily acceptable salts thereof, having high affinity in vitro for D2, 5-HT2, 1 receptors and in vivo activity on central nervous system and antihypertensive activity with negligible secondary effects; methods for the preparation thereof; pharmaceutical formulations containing them.</p>
申请公布号 EP0379990(A1) 申请公布日期 1990.08.01
申请号 EP19900101080 申请日期 1990.01.19
申请人 ISTITUTO LUSO FARMACO D'ITALIA S.P.A. 发明人 SALIMBENI, ALDO;CASCIO, GIUSEPPE;MANGHISI, ELSO
分类号 A61K31/41;A61K31/4427;A61K31/455;A61K31/495;A61P9/00;A61P9/12;A61P25/18;A61P25/20;A61P25/24;A61P25/26;C07D233/70;C07D401/06;C07D401/14 主分类号 A61K31/41
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