| 发明名称 |
COMPOSITION FOR THE TRANSDERMAL DELIVERY OF FENTANYL |
| 摘要 |
A transdermal drug delivery composition comprises an acrylate copolymer and from about 8% to about 30% by weight fentanyl. A transdermal fentanyl delivery composition comprising methyl laurate or tetraglycol as a permeation enhancer is also provided. The transdermal drug delivery compositions can be used to make a transdermal drug delivery device for the delivery of fentanyl. |
| 申请公布号 |
US2016184235(A1) |
申请公布日期 |
2016.06.30 |
| 申请号 |
US201615064877 |
申请日期 |
2016.03.09 |
| 申请人 |
3M Innovative Properties Company |
发明人 |
Cantor Adam S.;Ocheltree Terrance W.;Robles Cynthia A. |
| 分类号 |
A61K9/70;A61K9/00;A61K31/4468 |
主分类号 |
A61K9/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A transdermal patch for administering fentanyl through the skin comprising:
(a) a backing layer; and (b) a polyacrylate adhesive reservoir disposed on the backing layer, at least the skin contacting surface of said reservoir being adhesive; comprising a single phase polymeric composition free of undissolved fentanyl and containing an amount of fentanyl sufficient to induce and maintain analgesia in a human for at least three days. |
| 地址 |
St. Paul MN US |
