Process for the preparation of 4-alkoxyalkyl beta -carbolines

摘要

A process is disclosed for the preparation of 4-alkoxyalkyl beta -carboline derivatives of general Formula I <IMAGE> I wherein R1 is hydrogen or methyl, R2 is an optionally substituted aliphatic hydrocarbon residue, R3 is lower alkyl, and RA is hydrogen, halogen, COOR4 or OR5, R4 meaning lower alkyl and R5 meaning hydrogen, lower alkyl, cycloalkyl, or optionally substituted pheny, by reaction of a compound of Formula II in the presence of AgBF4 with an alcohol of the formula R2OH wherein R2 has the meanings given above.