RETROVIRAL VECTOR AND ITS USE IN THE PRODUCTION OF TRANSGENIC ANIMALS

摘要

2045480 9008832 PCTABS00001 Retroviral vectors carrying foreign nucleic acid and having a Feline Leukaemia Virus B env gene product can be introduced into the embryos of sheep and pigs. The foreign nucleic acid is incorporated into the embryo chromosomes, producing transgenic animals. Introduction of a retroviral vector into any embryo is improved by injecting it through the zona pellucida into the perivitelline space.