发明名称 DERIVATIVES OF POLYHYDROXYLATED MOLECULES FOR INTRODUCING AT LEAST ONE RAMIFICATION IN AN OLIGONUCLEOTIDE
摘要 <p>The invention relates to derivatives of polyhydroxylated molecules having the formula (Ia) or the formula (Ib) wherein R1 is a protector radical of a group OH appropriate for the oligonucleotidic synthesis, R2 is a functional radical adapted to the oligonucleotidic synthesis, unsubstituted or substituted by OR1, B is a radical derived from a puric or pyrimidic base comprising at least one substituant OR1. When such derivative is used in oligonucleotidic synthesis, it is possible to fix by means of said radicals OR1 a plurality of nucleotides, molecules of spaces or molecules or markers and the polyhydroxylated derivative, and thus form an oligonucleotide comprising at least one ramification.</p>
申请公布号 WO1990008156(A1) 申请公布日期 1990.07.26
申请号 FR1990000043 申请日期 1990.01.19
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