摘要 |
New benzopyran derivatives of general formula (I) in which: R1 denotes a hydrogen or halogen atom or a hydroxy, alkyloxy, nitro, amino, alkylsulphonamido, bis(alkylsulphonyl)amino, or acylamino radical, R denotes a radical of general formula: <IMAGE> in which A denotes a single bond or a methylene radical and R2 and R3 which may be identical or different, denote a hydrogen or halogen atom or a hydroxy, alkyl, alkyloxy, nitro, amino, alkylsulphonamido, bis(alkylsulphonyl)amino, acylamino, sulphamoyl or cyano radical, or form together, when they are adjacent, a methylenedioxy or ethylenedioxy radical, or alternatively R denotes a 2-oxo-2H-benzimidazolyl radical, and R' and R'' are identical and denote hydrogen atoms or alkyl radicals, their isomeric forms and their preparation. These new products are useful as antiarrhythmic and antifibrillating agents. <IMAGE> (I) |