发明名称 MEDICAMENT FOR THE TREATMENT OF DISEASES CAUSED BY RETROVIRUSES
摘要 The invention relates to the use of amino acid derivatives which inhibit the activity of retroviral proteases and have the structural element of the formula I -NR<1>-CHR<2>-CR<3>-(CHR<4>)n-CO- in which R<1>, R<4>, R<5> and R<6> are each H or alkyl, R<2> is H, alkyl, in each case substituted or unsubstituted aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, het or het-alkyl, R<3> is (H, OH), (H, NR<5>R<6>) or O, het is a 5- or 6-membered N-, S- or O-containing saturated or unsaturated heterocycle and n is 1 or 2, or of the physiologically acceptable salts thereof for treating diseases caused by retroviruses.
申请公布号 ZA8907549(B) 申请公布日期 1990.07.25
申请号 ZA19890007549 申请日期 1989.10.04
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 PETER RADDATZ;CLAUS J. SCHMITGES;KLAUS E. VON DER HELM
分类号 A61K31/195;A61K31/33;A61K38/00;A61K38/04;A61K38/55;A61P31/12;A61P31/18 主分类号 A61K31/195
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