| 摘要 |
Unsymmetrical organic disulfide sulfinate compounds, useful as an antiradiation agents, having the general formula: <IMAGE> wherein A is one or of the following polar groups, OH, COOH, SO3Na, -C(O)-, or derivatives such as esters and nonamino nitrogen derivatives such as amides or nitriles; k is an integer of one to eight; Y is a straight or substituted aliphatic chain having from two to eight carbon atoms which may have one or more S-S groups interposed therebetween; m signifies the number of carbon atoms in an aliphatic chain Y containing 2 to 8 carbon atoms which may have S-S interposed; aliphatic chain Y, substituted with one or more polar groups of the number k is attached to one of the two sulfur atoms shown. The second sulfur atom is attached through an aliphatic chain of 2 to 5 carbon atoms to the sulfinate function SO2M wherein R1 and R2 may be hydrogen, aryl, cycloalkyl or various polar groups such as OH, COOH, SO3Na, -C(O)-, or derivatives such as esters and nonamino derivatives such as amides or nitriles. The system <IMAGE> also may comprise an aromatic ring; n may be the integers 2 through 6; M of the sulfinate function is hydrogen, a metallic element selected from group 1 A of the Periodic Table such as Li, Na, or K, or the equivalent R4N+; or an organic group such as a straight or substituted aliphatic chain having up to 4 carbon atoms, designed to promote stability. The synthesis of the compounds occurs by subjecting 1,1-dioxides of cyclic disulfides to the action of a thiolate ion, whereby cleavage is effected between the sulfur and sulfonyl units.
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