Water-soluble derivatives of camptothecin have the formulae: <IMAGE> (3) wherein R' is selected from the group consisting of R=CO CH2NH2.HCl R=CO CH2NHCH3.HCl R=CO CH2NHC2H5.HCl R=CO CH2 N(C2H5)2.HCl R=CO CH(NH2) CH2CH2CH2CH2CH2NH2.2HCl R=CO CH(NH2) CH2CH2COOH. HCl R=CO CH2CH2.COO- Na+ R=HPO3- Na+
申请公布号
US4943579(A)
申请公布日期
1990.07.24
申请号
US19870104894
申请日期
1987.10.06
申请人
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
