发明名称 PROCESS FOR DISSOLVING OFF AN ANALYTE FROM ITS BINDING PROTEIN
摘要 The method entails the binding protein being degraded by a thiol which cleaves SH groups in the alkaline range and is characterised in that a 1,2-dithiolane-3-carboxylic acid of the formula (I) <IMAGE> in which n is an integer from 1 to 8, is used as thiol which cleaves SH groups, and the method is used to prepare samples for analytical and investigative methods for determining the liberated analyte, in particular for immunoassays for vitamin B12.
申请公布号 AU4768590(A) 申请公布日期 1990.07.19
申请号 AU19900047685 申请日期 1990.01.04
申请人 BOEHRINGER MANNHEIM GMBH 发明人 NICHOLAS R. HOYLE
分类号 C07D339/04;C07K1/107;C07K14/435;C07K14/575;C07K16/00;G01N33/74;G01N33/78;G01N33/82 主分类号 C07D339/04
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