摘要 |
PURPOSE:To provide a transcutaneous absorbefacient containing extract of crude drugs such as SHOZUKU (fruit of Elettoria cardamomum), SHOUKYOU (rhizome of Zingiber officinale), OUBAKU (bark of Phellodendron amurense) and KEIHI (bark of Cinnamomum cassia). CONSTITUTION:Crude drugs such as SHOZUKU, SHOUKYOU, OUBAKU or KEIHI are dried, crushed and immersed in 10 pts. (based on 1 pt. of the crude drug) of a cold solvent such as acetone, ether, ethyl acetate or water for 3 days, and the solvent extraction process is repeated thrice. The extract is filtered and then concentrated in vacuum at <=40 deg.C and the obtained dried extract is used as a component of the objective agent. Acetone extract especially has excellent transcutaneous absorbability and the agent is used in the form of a liquid spray, lotion, ointment, cream, aerosol, poultice, tape, etc. Examples of the agent increasing the drug action by the use of the above agent are anti- inflammatory, antihistaminic, sulfamides, antibiotic substance, antimycotic agent, anti-malignant tumor agent, narcotic agent, psychotropic agent, etc. |