发明名称 |
Quinoline carboxylic acid boric acid anhydrides |
摘要 |
PCT No. PCT/HU88/00018 Sec. 371 Date Dec. 2, 1988 Sec. 102(e) Date Dec. 2, 1988 PCT Filed Apr. 8, 1988 PCT Pub. No. WO88/07998 PCT Pub. Date Oct. 20, 1988.The invention relates to new quinoline-3-carboxylic acid anhydride intermediates of the Formula I <IMAGE> (I) wherein R stands for cyclopropyl, a group of the Formula -CH2CR5R6R7 wherein R5, R6 and R7 stand for hydrogen or halogen, or phenyl optionally substituted by 1 or 2 halogen, R1 and R2 stand for halogen, or an aliphatic acyloxy group containing 2 to 6 carbon atoms optionally substituted by halogen, or an aromatic acyloxy group containing 7 to 11 carbon atoms, R3 stands for chlorine or fluorine and R4 stands for hydrogen or fluorine. The compounds of the Formula I are new intermediates for the preparation of known quinoline-3-carbocxylic acids showing antibacterial activity.
|
申请公布号 |
US4940794(A) |
申请公布日期 |
1990.07.10 |
申请号 |
US19880290167 |
申请日期 |
1988.12.02 |
申请人 |
CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA/RT. |
发明人 |
HERMECZ, ISTVAN;KERESZTURI, GEZA;VASVARI, LELLE;HORVATH, AGNES;HALOGH, MARIA;RITLI, PETER;SIPOS, JUDIT;PAJOR, ANIKO;MARMAROSI, KATALIN |
分类号 |
C07D215/56;A61K31/47;A61P31/04;C07D215/16;C07D215/54;C07F5/00;C07F5/02;C07F5/04 |
主分类号 |
C07D215/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|