摘要 |
Cephalosporin compounds of the formula: <CHEM> wherein R<1> is amino or protected amino; R<2> is substituted or unsubstituted heterocyclic group having 1 - 3 hetero atoms selected from oxygen and sulphur; R<3> is carboxyl or protected carboxyl; R<4> is nucleophilic compound residue; R<5> is carboxyl, protected carboxyl and -COO<->, a pharmaceutically acceptable salt thereof and their synthetic intermediate of the formula: <CHEM> wherein R<1><1> is amino or protected amino; R<2> is substituted or unsubstituted heterocyclic group having 1 - 3 hetero atoms selected from oxygen and sulfur; R<3> is carboxyl or protected carboxyl; -COOY is carboxyl or protected carboxyl. Said cephalosporin compound is useful as antibacterial agent. |