CERTAIN ARALKYLAMINOALKYL ESTERS OF 1,4 DIHYDROPYRIDINES AS ANTIHYPERTENSIVE

摘要

1,4-DIHYDROPYRIDINE DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF A 1,4-dihydropyridine derivative of the formula wherein R1 and R2 are identical or different and each represents a hydrogen atom, a halogen atom or a nitro group, provided that R1 and R2 are not hydrogen atoms at the same time; R3 represents an alkyl group; R4 represents an aralkyl group which may be substituted; R5 and R7 are identical or different and each represents an alkyl group; R6 represents a hydrogen atom or an alkyl group; R9 represents an alkyl group; R9 represents a hydrogen atom or an alkyl group; n and m are identical or different and each represents an integer of O to 6; provided that when either one of R1 and R2 is a hydrogen atom, R9 is an alkyl group; or an acid addition salt thereof. The 1,4-dihydropyridine derivative is characterized by a strong antihypertensive activity and the long duration of the activity.