发明名称 |
METHOD FOR TRANSFORMING HUMAN B LYMPHOCYTES |
摘要 |
Disclosed herein is a method for transforming human B-cells preferably by infecting them with Epstein-Barr virus followed by transforming the Epstein-Barr virus infected cells with an activated human ras gene. The transformed cells are useful for producing human monoclonal antibodies either without further manipulation or after fusion with antibody-secreting cells. |
申请公布号 |
WO9006994(A1) |
申请公布日期 |
1990.06.28 |
申请号 |
WO1989US05885 |
申请日期 |
1989.12.15 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
DALLA-FAVERA, RICCARDO;SEREMITIS, STEPHANIE |
分类号 |
C12N15/09;C12N5/10;C12N5/16;C12N15/02;C12P21/08;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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