Plasma cholesterol level lowering medicaments.

摘要

The instant invention is directed to a use of an HMG-CoA reductase inhibitor for the prepartion of a medicament adapted for time-controlled administration, useful for enhancing the lowering of plasma cholesterol levels, such that the medicament affords an equivalent or improved reduction of plasma cholesterol levels while significantly reducing the amount of HMG-CoA reductase inhibitor circulating in the bloodstream of a subject when compared to the oral administration of conventional rapid release dosage form.