3-SUBSTITUTED CARBACEPHEM COMPOUND AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

摘要

Carbacephem compounds represented by the formula: [wherein R1 is a lower alkylsulfonyloxy, unsubstituted or substituted arylsulfonyloxy, azido, cyano, carbamoyloxy, unsubstituted or substituted heterocyclic thio ("heterocyclic" means a 5- or 6-membered heterocyclic group having 1 to 4 O, S or N atoms), unsubstituted or substituted lower alkylthio, or unsubstituted or substituted arylthio group; R2 and R3 are groups frequently used in the cephalosporin chemistry] have strong antibacterial activity against Gram-positive and Gram-negative bacteria, and are useful for curing various infections.