| 发明名称 |
S-Diastereomer of N6-¬(2-hydroxy-propyl)aryl adenosines |
| 摘要 |
<p>A novel S diastereomer of an N<6>-(2-hydroxypropyl)aryl] adenosine (I), which diastereomer exhibits fewer CNS side effects than the racemate, but with no decrease in cardiovascular activity. The invention further provides for compositions incorporating the diastereomer, and methods of its use, as well as pharmaceutically acceptable salts thereof. <CHEM> 6</p> |
| 申请公布号 |
EP0374425(A1) |
申请公布日期 |
1990.06.27 |
| 申请号 |
EP19890119668 |
申请日期 |
1989.10.24 |
| 申请人 |
G.D. SEARLE & CO. |
发明人 |
LOWRIE, HARMAN SMITH;WALSH, GERALD MICHAEL |
| 分类号 |
A61K31/7042;A61K31/10;A61K31/70;A61K31/7052;A61K31/7076;A61P9/08;A61P9/12;C07H19/16;C07H19/167 |
主分类号 |
A61K31/7042 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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