摘要 |
<p>Compounds of formula I, <CHEM> in which R1 represents OH, NR11R21, CH2R12, or fluorine, W represents a single bond, 1,2-,1,3- or 1,4-phenylene; a -CH=CH-group or a 1,4-cyclohexanediyl group; X represents NH, 0, S, SO2, CO, CH2, CONH or -COO; Y represents inter alia (CH2)q, CO, CS or SO2 Z represents a single bond, NR19, CH2, 0, CO, S or SO2, and the other terms are as defined in the specification, and pharmaceutically acceptable derivatives thereof, possess useful pharmacological activity.</p> |