发明名称 Sulphonic acid substituted aromatic steroids as inhibitors of steroid 5-alpha-reductase.
摘要 <p>Compounds of structure (I) &lt;CHEM&gt; in which the dotted lines indicate the optional presence of a double bond, X&lt;1&gt;, X&lt;2&gt; and X&lt;3&gt; are H, halogen, CF3, C1-6alkyl, C1-6alkoxy, CN, NO2, N(R&lt;1&gt;)2, CHO or CO2R&lt;1&gt;; R&lt;1&gt; is H or C1-8alkyl and R is hydrogen, hydroxy or acetoxy; processes for their preparation, compositions containing them and their use in medicine as inhibitors of 5- alpha -reductase.</p>
申请公布号 EP0375347(A1) 申请公布日期 1990.06.27
申请号 EP19890313260 申请日期 1989.12.19
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 HOLT, DENNIS ALAN;METCALF, BRIAN WALTER;LEVY, MARK ALAN
分类号 A61K31/56;A61P5/00;C07J31/00;C07J41/00 主分类号 A61K31/56
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