摘要 |
Compounds of structure (I): <CHEM> in which R<1> is hydrogen, C1-6alkyl, C1-6alkoxy, C1-6alkoxy-C1-6-alkyl, C3-6cycloalkyl, C3-6cycloalkylC1-6alkyl, phenyl, phenylC1-6alkyl, the phenyl groups being optionally substituted; R<2> is hydrogen, C1-6alkyl, C1-6alkoxy, amino C1-6alkylthio, halogen, cyano, hydroxy, carbamoyl, carboxy, C1-6alkanoyl or trifluoromethyl; m is 1 to 3; p is 0 to 4; R<3> is COR<4>; R<4> is hydroxy, C1-6alkoxy or NR<5>R<6>; R<5> and R<6> are each hydrogen or C1-6alkyl or together with the nitrogen atom to which they are attached form a heterocyclic ring; and R<7> is hydrogen, hydroxy, C1-6alkoxy or C1-6alkyl, processes for preparing them, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy as inhibitors for gastric acid secretions. |