发明名称 5-(AZOLYLOXYPHENYLCARBAMOYL)BARBITURIC ACID DERIVATIVES AS ANTHELMINTICS
摘要 The invention relates to novel 5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives of the general formula I <IMAGE> (I) wherein X is oxygen or sulfur; R1 is C1-C6alkyl, C1-C6alkoxy, C3-C6cycloalkyl or allyl; R2 is C1-C6alkyl or allyl; R3 is an unsubstituted or substituted five-membered azole ring which is bound through carbon and is selected from the group consisting of benzimadazole, benzoxazole, benzothiazole, imidazole, oxazole, thiazole, oxadiazole, thiadiazole and triazole; and R4 and R5 are each independently of the other hydrogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy or C1-C6haloalkoxy; and to the tautomers and salts thereof, as anthelmintic compounds. Together with suitable carriers and further assistants, these compounds may be used in particular for controlling helminths which are parasites of animals.
申请公布号 PH24423(A) 申请公布日期 1990.06.25
申请号 PH20050000334 申请日期 1986.02.11
申请人 CIBA-GEIGY AG. 发明人 ELMAR STURM;JEAN JAQUES GALLAY;HAUKUR KRISTINSSON;GEORG PISSIOTAS
分类号 C07D263/58;A61K31/496;A61K31/515;A61P33/10;C07D233/70;C07D235/26;C07D239/62;C07D239/66;C07D249/08;C07D249/12;C07D271/06;C07D271/10;C07D271/113;C07D277/24;C07D277/34;C07D277/58;C07D277/68;C07D285/08;C07D285/12;C07D285/13;C07D403/12;C07D413/12;C07D417/12 主分类号 C07D263/58
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