| 摘要 |
The invention relates to the use of compounds of the type of renin inhibitors or of related aspartate proteinase inhibitors as gag protease inhibitors. It particularly relates to the use of these compounds for preparing pharmaceutical products for use as gag protease inhibitors, in which case compounds of the formula R<2>-AAN-Q-AAC-R<1> (I> in which AAN is a divalent radical which consists of 1 to 5 divalent alpha -amino acid residues and which is connected at the N terminus to the radical R<2> and at the C terminus to the radical Q, AAC is a bond or a divalent radical which consists of one to five divalent alpha -amino acid residues and which is connected at the N terminus to the radical Q and at the C terminus to the radical R<1>, R<1> is hydroxyl, etherified hydroxyl, amino or substituted amino with the exception of an amino radical derived from an alpha -amino acid, R<2> is hydrogen or an acyl radical with the exception of an optionally N-substituted acyl radical of a natural amino acid, and Q is a divalent radical which is an isostere of a dipeptide, and salts thereof, are used. |
