METHOD FOR DISRUPTING VIRUS PARTICLES

摘要

TITLE: METHOD FOR DISRUPTING VIRUS PARTICLES Disclosed is a method for disrupting virus particles comprising subjecting the virus particles to high-speed collision treatment, preferably using a Microfluidizer (registered trade mark), thereby being capable of disrupting the virus particles without damaging the partial structure of viral envelopes thereof, which results in the preparation of an influenza vaccine high in immunogenicity (potency) and having no pyrogenicity.