| 摘要 |
PURPOSE:To obtain a hair tonic, containing a specific pyrimidine N-oxide derivative and having excellent alopecic preventive and trichogenous effects. CONSTITUTION:A hair tonic containing 0.001-15wt.%, preferably 0.1-10wt.% compound expressed by the formula (R1 and R2 are H, 1-4C alkyl or 2-4C alkenyl; R3 and R4 are H, 1-8C alkyl, 3-7C alkenyl or, together with N, may form aziridinyl, azetidinyl, pyrrolidinyl, piperidino, hexahydroazepinyl, heptamethyleneimino, octamethyleneimino or morpholino, provided that both are not simultaneously H), acylated substance, tautomer or acid addition salt thereof, e.g. 2,4-diamino-6-piperidino-1,3,5-triazine-3-oxide. The daily dose of the above-mentioned hair tonic is within the range of 0.001-100mg, preferably 0.1-10mg per kg body weight. |
