发明名称 Anti-inflammatory 5-hydroxy-2-furanones.
摘要 <p>The invention provides compounds of the formula (I): &lt;CHEM&gt; in which: R is hydrogen, C1-C14 alkanoyl, CONHR3 or CO2R4: R3 is H, phenyl or C1-C4alkyl; R4 is C1-C6 alkyl; A is CH2O-R1 or &lt;CHEM&gt; when R is C1-C14 alkanoyl, A may be CH2OCOR2 or CH2OP(O)(OR2)R2; R1 is C7-C14 alkanoyl, N-(C6-C14 alkyl) carbamoyl, naphthyl-(C1-C6 alkylene), pyridyl-(C1-C6 alkylene) or methoxyethoxymethoxymethyl; and R2 is C1-C4 alkyl; pharmaceutical compositions containing them, processes for their preparation, and their use in the treatment of inflammation, allergic response and psoriasis.</p>
申请公布号 EP0372941(A2) 申请公布日期 1990.06.13
申请号 EP19890312738 申请日期 1989.12.07
申请人 ALLERGAN, INC 发明人 LEE, GARY C. M.
分类号 A61K31/365;A61K31/44;A61K31/443;A61P29/00;C07D307/60;C07D405/12;C07F7/08;C07F9/655;C07F9/6558 主分类号 A61K31/365
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