发明名称 Cyclosporine binding protein and its use in an assay for biologically-active cyclosporine.
摘要 <p>A method of quantitatively estimating biologically-active cyclosporines, analogues, derivatives and metabolites by a competitive protein binding assay uses water-soluble binding proteins isolated from the cycloplasm of human and animal cells. Tracers include radioactive atoms, fluorescent molecules, enzymes, and chemiluminescent molecules. Solution and solid phase assay methods are disclosed. Also claimed are the water-soluble binding proteins.</p>
申请公布号 EP0372862(A2) 申请公布日期 1990.06.13
申请号 EP19890312578 申请日期 1989.12.01
申请人 CHILDREN'S NATIONAL MEDICAL CENTER, INC. 发明人 SOLDIN, STEVEN J.
分类号 G01N33/53;A61K38/00;C07K14/005;C07K14/195;C07K14/37;C07K14/41;C07K14/705;C12Q1/34;C12Q1/42;G01N21/78;G01N33/94 主分类号 G01N33/53
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