发明名称 |
ANTIBODIES SPECIFIC FOR ELAM-1 AND THE USE THEREOF |
摘要 |
The invention relates to a method for detecting ELAM-1 expression in a patient comprising (i) administration of a detectable amount of a labelled ELAM-1 specific antibody (or an anti-ELAM 1 antibody fragment) and a pharmaceutically acceptable carrier, and (ii) detecting the label. ELAM-1 is an endothelial cell surface glycoprotein which participates in endothelialleukocyte adhesion. Induction of ELAM-1 expression has been detected on endothelial cells at sites of inflammation. |
申请公布号 |
AU4621789(A) |
申请公布日期 |
1990.06.12 |
申请号 |
AU19890046217 |
申请日期 |
1989.11.14 |
申请人 |
BRIGHAM AND WOMEN'S HOSPITAL |
发明人 |
MICHAEL P. BEVILACQUA;MICHAEL A. GIMBRONE |
分类号 |
G01N33/53;A61K38/00;A61K39/395;A61K45/00;A61K47/48;A61K51/00;A61P29/00;A61P31/04;A61P35/00;C07K14/00;C07K14/705;C07K16/00;C07K16/28;C12N15/09;C12P21/08 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|