INDENE COMPOUNDS

摘要

The invention provides an indene compound represented by the following general formula (I): (I) wherein R1 means a lower alkyl group, R2 and R3 denote a lower alkyl group individually or an alkylenedioxy group in combination, and R4 and R5 mean individually a substituted or unsubstituted lower alkyl or aryl group or in combination a substituted or unsubstituted piperidino, piperazinyl or homopiperazinyl group together with the adjacent nitrogen atom, with a proviso that not both R4 and R5 are a methyl group at the same time. The compounds of this invention have the ability to increase coronary blood flow and thus are useful as therapeutic agents for angina pectoris.