Optical active (meth)acrylamides and polymers thereof for racemate resolution

摘要

In the chromatographic separation of a mixture of antipodes of optically active chemicals by passing a solution of such mixture over an optically active adsorbent to effect adsorption, and then eluting the adsorbed material, the improvement which comprises employing as the adsorbent particles of an optically active and cross-linked polymer containing the repeating structural unit <IMAGE> in which R1 represents hydrogen or methyl, and R2 represents one of the stereoisomers of the eight possible stereoisomeric forms of each of the optically active radicals of the formulae <IMAGE> Improved separation results. The pure monomers are also new.