发明名称 CONTROLLED RELEASE DELIVERY COATING FORMULATION FOR BIOACTIVE SUBSTANCES
摘要 The present invention relates to a bioactive composition having a controlled, sustained release delivery pattern when contacted with a suitable surrounding media. The composition comprises a pharmaceutically, insecticidally, herbicidally or fertilizing bioactive material core, soluble in a given surrounding media, the core present in an amount at least sufficient for a total dosage during a specified treatment period; a first coating enveloping the bioactive material core comprising a polymer or a blend of polymers, said polymer or blend of polymers being swellable upon penetration by the surrounding media; and a second coating enveloping the first coating, the second coating comprising a polymer or a blend of polymers being water-insoluble and forming a semi-permeable barrier to the inward diffusion of the surrounding media and the outward diffusion of the bioactive material dissolved in the surrounding media.
申请公布号 ZA8806551(B) 申请公布日期 1990.05.30
申请号 ZA19880006551 申请日期 1988.09.02
申请人 AIR PRODUCTS AND CHEMICALS, INC. 发明人 ANIL S. AMBEGOANKAR;ROGER ALAN HOWELLS
分类号 A61K9/52;A01N25/26;A61K9/28;A61K9/50;A61K9/54;A61K47/32;A61K47/38 主分类号 A61K9/52
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