发明名称 |
25, 28-dihydroxyergocalciferol and 1,25,28-trihydroxyergocalciferol compositions thereof and their use in the treatment of hyperproliferative disease |
摘要 |
Compounds of the formula <IMAGE> I wherein R'' is hydrogen or hydroxy, epimers at the 24-position of compounds of formula I, diastereomeric mixtures of compounds of formula I which are epimeric at the 24-position, and mixtures thereof, which are useful as agents for the treatment of psoriasis, and osteoporosis, are described.
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申请公布号 |
US4929609(A) |
申请公布日期 |
1990.05.29 |
申请号 |
US19880272170 |
申请日期 |
1988.11.14 |
申请人 |
HOFFMANN-LA ROCHE INC.;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF AGRICULTURE |
发明人 |
BATCHO, ANDREW D.;HORST, RONALD L.;USKOKOVIC, MILAN R.;NAPOLI, JOSEPH L. |
分类号 |
C07C35/21 |
主分类号 |
C07C35/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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