FIBRINOLYSIS-ENHANCING AGENTS

摘要

FIBRINOLYSIS-ENHANCING AGENTS Disclosed herein is a fibrinolysis-enhancing agent comprising, as an effective ingredient, an N2-arylsulfonyl- L-arginine amide represented by the general formula (I): ... ... (I) wherein R1 is a group of the formula: where R3 is an alkyl group having 3 to 5 carbon atoms or an alkoxyalkyl group having 2 to 4 carbon atoms and R4 is an alkyl group having 1 to 3 carbon atoms; and R2 is a group of the formula: where R5 and R6 are independently hydrogen atom, methyl group or methoxy group provided that they cannot be hydrogen atoms simultaneously, and R7 is an alkyl group having 1 to 3 carbon atoms; or a salt thereof. The agent is used in combination with a plasminogen activator.