发明名称 ANTIDOTE
摘要 PURPOSE: To cope with mammalian intoxication caused by flupropadine, a powerful rodenticide, or its relating compounds by using chlorpromazine, citalopram, fluoxetine or the like as an antidote. CONSTITUTION: As an antidote for mammalian intoxication with flupropadine, [1-(3,5-bistrifluoromethylphenyl)-3-(4-t-butylpiperidino)prop-l-yne], or its relating compounds, are used a tricyclic antidepressant agent (for example, chlorpromazine), citalopram, fluoxetine or their salts. These compounds adjusts the aminergicity system in the gastrointestinal tract and the adrenal tissues. This antidote may be given orally, rectally, subcutaneously, intramuscularly, nasally or percutaneously, but a single depot preparation or a multipump type implantation is suitable optimally for long-time application.
申请公布号 JPH02134330(A) 申请公布日期 1990.05.23
申请号 JP19890264094 申请日期 1989.10.12
申请人 WELLCOME FOUND LTD:THE 发明人 RATSUSERU NIKORUSON
分类号 C07D223/28;A61K31/00;A61K31/34;A61K31/445;A61K31/54;A61K31/55;A61K45/00;A61P39/02;C07D279/28;C07D307/87 主分类号 C07D223/28
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