Hybrid plasmids and microorganisms containing them

摘要

New hybrid plasmids which are useful as vectors in recombinant DNA in which Acremonium chrysogenum or Saccharomyces cerevisiae is used as a host, and microorganisms bearing the hybrid plasmids, are disclosed. The disclosure herein is based on the cloning of autonomous replication sequences (ARS) of A. chrysogenum ATCC 11550 and introduction of the ARS into a shuttle vector of E. coli and Saccharomyces cerevisiae and construction of new types of plasmids based on the ARS.