发明名称 METHOD FOR THE SYNTHESIS OF 1-CYCLOPROPYL-6-FLUORO-1,4 DIHYDRO-4-OXO-7-CHLORO-QUINOLINE-3-CARBOXYLIC ACID AS BASIS FOR THE PREPARATION OF 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-PIPERAZINE-QUINOLINE-3-CARBOXYLIC ACIDS
摘要 <p>A method of preparation is described for 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-chloro-kinolin-3-carboxylic acid: [chemical formula] as well as the reaction process of the acid (I) with piperazine, or its derivatives of the formula: [chemical formula], where R = methyl, ethyl, benzyl, pyridyl, hydrogen. Transformations of these new piperazinic derivatives to acidic additive salts are distinguished for their antibacterial properties and are pharmaceutically useful.</p>
申请公布号 GR880100409(A) 申请公布日期 1990.05.11
申请号 GR19880100409 申请日期 1988.06.23
申请人 TSETIS KLEON 发明人 TSETIS KLEON
分类号 C07D215/56;(IPC1-7):C07D215/56 主分类号 C07D215/56
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