摘要 |
<p>Antimicrobial quinolonyl lactam esters comprising a lactam-containing moiety linked, by an ester group, to the 3-carboxy group of a quinolone moiety. These compounds are of formula (I), wherein (1) R?3, R4, and R5¿, together with bonds ''a'' and ''b'', form certain lactam-containing moieties similar to those known in the art to have antimicrobial activity; and (2) A, R?6, R7, and R8¿ form any of a variety of quinolone or napthyridine structures similar to those known in the art to have antimicrobial activity.</p> |