SPECIFIC REMOVAL OF LDL FROM BLOOD

摘要

Disclosed herein are particularly efficient methods to reduce cholesterol in patients by treating whole blood with agarose beads conjugated to anti-LDL antibodies or, especially when conjugated through the mediation of an amino functionality, to a polyanionic sulfate. In preferred embodiments, the beads are characterized as comprising 0.5-3 % agarose, preferably 2 % agarose, and having diameters of 200-300 micron. Preferred antibodies are cross-reactive with C3D1 antibodies.