发明名称 NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS THERAPEUTICALS
摘要 The present invention relates, by way of novel industrial products, to the beta -D-phenylthioxyloside compounds of the formula <IMAGE> (I) in which: X represents a sulfur atom or an oxygen atom; R1, R2 and R3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group -CO-R (in which R represents a C1-C4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH3), a C1-C4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for R1 and R2, taken together, to form, with the phenyl group to which they are bonded, a beta -naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; and Y represents the hydrogen atom or an aliphatic acyl group. These compounds are useful as therapeutic agents, especially as venous antithrombotics.
申请公布号 AU4356089(A) 申请公布日期 1990.04.26
申请号 AU19890043560 申请日期 1989.10.17
申请人 FOURNIER INNOVATION ET SYNERGIE 发明人 SOTH SAMRETH;JEAN MILLET;FRANCOIS BELLAMY;JERZY BAJGROWICZ;VERONIQUE BARBEROUSSE;PATRICE RENAUT
分类号 C07H5/02;A61K31/70;A61K31/7024;A61K31/7028;A61K31/7034;A61P7/02;C07C323/09;C07C323/62;C07C333/04;C07H5/10;C07H13/00;C07H13/04;C07H15/14;C07H15/203 主分类号 C07H5/02
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