| 摘要 |
The use of at least one compound of Formula (I) for the manufacture of a medicament for controlling and/or reducing a patient's serum cholesterol and/or triglyceride level is disclosed. <CHEM> wherein Y is O or NH, R is OH, NHCONR<4>R<5>; or N=C(NR<4>R<5>)2;where R<4> and R<5> are each independently selected from the group consisting of hydrogen; C1-10alkyl, straight or branched chain; aryl C1-4alkyl; mono- or disubstituted aryl C1-4 alkyl where the substituents are fluoro, chlore, bromo, iodo, or C1-10alkyl, straight or branched chain; R<1> and R<2> are each independently selected from the group consisting of hydrogen, animo, and mono- or di-substituted amino where the substituents are C1-10alkyl, straight or branched chain, C3-8 cycloalkyl; provided that R<1> and R<2> may not both be amino or substituted amino and; R<3> is hydrogen, trifluoromethyl, fluoro; chloro, bromo, or iodo, or a pharmaceutically acceptable salt thereof. e |
