发明名称 |
Method of, and apparatus for, NMR spectroscopic metabolite imaging and quantification. |
摘要 |
<p>A method for NMR spectroscopy metabolite imaging utilizes the steps of: applying to a desired portion of a sample a pulsed phase-encoding linear magnetic gradient signal in at least one of the three orthogonal dimensions of a Cartesian coordinate set, prior to acquisition of free-induction-decay NMR response signals from the sample portion; substantially eliminating from at least the sample portion eddy current fields induced responsive to the phase-encoding gradient pulses; maximizing the signal-to-noise ratio of the NMR response signals; and displaying the data resulting from Fourier transformation of the received response data. A high-field imaging system is provided with self-shielded gradient coils, to substantially remove eddy-current effects, and at least one of maximized-SNR antenna, of quadrature-driven volume RF coil and/or surface RF coil types are utilized for both transmission of the excitation RF pulses and reception of the RF response signals. The acquired FID data is filtered and a Fourier transform reconstruction, of dimension d min equal to one greater than the number d of spatial dimensions to be displayed, is performed.</p> |
申请公布号 |
EP0365352(A2) |
申请公布日期 |
1990.04.25 |
申请号 |
EP19890310840 |
申请日期 |
1989.10.20 |
申请人 |
GENERAL ELECTRIC COMPANY |
发明人 |
BOTTOMLEY, PAUL ARTHUR;EDELSTEIN, WILLIAM ALAN;ROEMER, PETER BERNARD;MUELLER, OTWARD MARIA |
分类号 |
A61B5/055;G01R33/36;G01R33/48;G01R33/485 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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