| 摘要 |
<p>In known electrophoresis apparatus, the directional modulation of the electric field used in electrophoresis is limited by the configuration of the electrode arrays. In the present invention, greater flexibility in directional modulation of an electric field is provided. Apparatus according to the invention comprises a support (20, 22, 24, 26, 28) in which a medium for electrophoresis is placed, the medium being in the form of a gel (G) and a liquid buffer. A plurality of driving electrodes (Dn) are arrayed in spaced relation to one another so as to contact the medium. A plurality of sensing electrodes (Sn) are also arrayed so as to contact the medium and are spaced relative to one another and to the driving electrodes. Each sensing electrode is preferably positioned radially inward of and paired with a single one of the driving electrodes. Electrical potentials are applied to selected ones of the driving electrodes (Dn) and means are provided for sensing electrical potentials at selected ones of the sensing electrodes (Sn) and for adjusting the applied potentials to maintain the sensed potential at a selected value at a sensing electrode of each pair. The apparatus may be programmably controllable so as to enable an electric field to be modulated in both amplitude and direction as a function of time.</p> |
