发明名称 Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides.
摘要 <p>Certain enol ethers and esters of the formula &lt;CHEM&gt; where X and Y are each hydrogen, fluoro or chloro; R&lt;1&gt; is 2-thienyl or benzyl and R is alkanoyl, cycloalkylcarbonyl, phenylalkanoyl, chlorobenzoyl, methoxybenzyl, phenyl, thenoyl, omega-alkoxycarbonylalkanoyl, alkoxycarbonyl, phenoxycarbonyl, 1-alkoxyalkyl, 1-alkoxycarbonyloxyalkyl, alkyl, alkylsulfonyl, methylphenylsulfonyl or dialkylphosphonate are useful as prodrug forms the known 3-acyl-2-oxindole-1-carboxamide antiinflammatory and analgesic agents.</p>
申请公布号 EP0365194(A2) 申请公布日期 1990.04.25
申请号 EP19890310319 申请日期 1989.10.09
申请人 PFIZER INC. 发明人 CRAWFORD, THOMAS CHARLES;REITER, LAWRENCE ALAN
分类号 C07D209/34;C07D409/06 主分类号 C07D209/34
代理机构 代理人
主权项
地址